TNF alpha Antikörper (Biotin)

Produktnummer ABIN6963904

Zitiert in 1 Publikation. Der Biotin-konjugierte Maus Monoklonal anti-TNF alpha Antikörper (Klon MT15B15) (ABIN6963904) detektiert spezifisch TNF alpha in WB, ELISA, FACS und ELISpot. Dieser Antikörper reagiert spezifisch mit Proben aus Non-Human Primate.

Kurzübersicht für TNF alpha Antikörper (Biotin) (ABIN6963904)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), ELISpot

Klon: MT15B15

Produktdetails anti-TNF alpha Antikörper (Biotin)

Spezifität: Native and recombinant TNF-α

Kreuzreaktivität (Details): The monoclonal antibody reacts with human TNF-α and cross-reacts with TNF-α from non-human primates.

Produktmerkmale: This monoclonal antibody enables specific detection of monkey TNF-α in immunoassays such as ELISpot, FluoroSpot, ELISA, flow cytometry, and Western blot. Serum/Plasma samples

Aufreinigung: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human TNF-alpha

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963898, ABIN6963901, ABIN6963902, ABIN6963904, ABIN7489162, ABIN6963905 and ABIN6963906 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963903 and ABIN7489161 . The antibody is also suitable for Western blot and Flow cytometry.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-TNF alpha Antikörper (Biotin) (ABIN6963904)

Phuah, Wong, Gideon, Maiello, Coleman, Hendricks, Ruden, Cirrincione, Chan, Lin, Flynn: "Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques." in: Infection and immunity, Vol. 84, Issue 5, pp. 1301-1311, (2017) (PubMed).

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNFA

Gen-ID: 7124

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome