TNF alpha Antikörper (Biotin)

Produktnummer ABIN6963900

Der Maus Monoklonal Anti-TNF alpha-Antikörper wurde für ELISA und ELISpot validiert. Er ist geeignet, TNF alpha in Proben von Human zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für TNF alpha Antikörper (Biotin) (ABIN6963900)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist konjugiert mit Biotin

Applikation: ELISA, ELISpot

Klon: MT20D9

Produktdetails anti-TNF alpha Antikörper (Biotin)

Spezifität: Native and recombinant TNF-α

Aufreinigung: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human TNF-alpha

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-TNF alpha Antikörper (Biotin) (ABIN6963900)

Herrera, Tsai, Chang, Hamel, Wang, Lu, Mboup, Kanki: "Sustained Specific and Cross-Reactive T Cell Responses to Zika and Dengue Virus NS3 in West Africa." in: Journal of virology, Vol. 92, Issue 7, (2018) (PubMed).

Bao, Wang, Liu, Shi, Lu, Sha, Weng, Hanabuchi, Qin, Plumas, Chaperot, Zhang, Liu: "NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells." in: The Journal of experimental medicine, Vol. 213, Issue 11, pp. 2383-2398, (2017) (PubMed).

McMahon, Banville, Bergin, Smedman, Paulie, Reeves, Kavanagh: "Activation of Neutrophils via IP3 Pathway Following Exposure to Demodex-Associated Bacterial Proteins." in: Inflammation, Vol. 39, Issue 1, pp. 425-433, (2016) (PubMed).

Sundström, Nguyen Hoang, Gupta, Ahlm, Svensson, Klingström: "Andes Hantavirus-Infection of a 3D Human Lung Tissue Model Reveals a Late Peak in Progeny Virus Production Followed by Increased Levels of Proinflammatory Cytokines and VEGF-A." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149354, (2016) (PubMed).

Snyder-Cappione, Tincati, Eccles-James, Cappione, Ndhlovu, Koth, Nixon: "A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males." in: PLoS ONE, Vol. 5, Issue 11, pp. e15412, (2011) (PubMed).

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNFA

Gen-ID: 7124

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome