TNF alpha Antikörper (Biotin)

Produktnummer ABIN6963897

Der Ratte Monoklonal Anti-TNF alpha-Antikörper wurde für ELISA und ELISpot validiert. Er ist geeignet, TNF alpha in Proben von Maus zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für TNF alpha Antikörper (Biotin) (ABIN6963897)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist konjugiert mit Biotin

Applikation: ELISA, ELISpot

Klon: MT11B10

Produktdetails anti-TNF alpha Antikörper (Biotin)

Spezifität: Natvie and recombinant TNF-α

Aufreinigung: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant mouse TNF-alpha

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-TNF alpha Antikörper (Biotin) (ABIN6963897)

Chen, Chen, Ren, Xia, Zhu, Liu, Zhang, Tang, Sun, Liu, Dong: "Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease." in: Kidney international, Vol. 96, Issue 2, pp. 409-420, (2020) (PubMed).

Li, Yan, Huang, Chi, Xu, Li, Liu, Feng, Wang, Zhao, Yang, Xia: "Characterization of the Immune Response of MERS-CoV Vaccine Candidates Derived from Two Different Vectors in Mice." in: Viruses, Vol. 12, Issue 1, (2020) (PubMed).

Shekar, Ramlal, Jeyabalaji, Sripathy: "Intranasal immunization of cocktail/fusion protein containing Tir along with ΔG active fragment of Zot as mucosal adjuvant confers enhanced immunogenicity and reduces E. coli O157:H7 shedding in mice." in: International immunopharmacology, Vol. 63, pp. 211-219, (2018) (PubMed).

Chida, Hara, Yano, Uchiyama, Das, Takahashi, Miyata, Tomioka, Ito, Kido, Sakaguchi: "Prion protein protects mice from lethal infection with influenza A viruses." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007049, (2018) (PubMed).

Abbassi-Daloii, Yousefi, Sekhavati, Tahmoorespur: "Impact of heat shock protein 60KD in combination with outer membrane proteins on immune response against Brucella melitensis." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 126, Issue 1, pp. 65-75, (2018) (PubMed).

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNFA

Gen-ID: 21926

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome