IL-6 Antikörper (Biotin)

Produktnummer ABIN6963872

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch IL-6 in ELISA und ELISpot. Er zeigt eine Reaktivität gegenüber Human und Non-Human Primate und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für IL-6 Antikörper (Biotin) (ABIN6963872)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Human, Non-Human Primate

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, ELISpot

Klon: 39C3

Produktdetails anti-IL-6 Antikörper (Biotin)

Spezifität: Native and recombinant IL-6

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with IL-6 from non-human primates.

Produktmerkmale: This monoclonal antibody enables specific detection of human IL-6 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human IL-6

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963872 and ABIN7448315 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963871, ABIN7448314 and ABIN6964024 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-IL-6 Antikörper (Biotin) (ABIN6963872)

Järver, Dondalska, Poux, Sandberg, Bergenstråhle, Sköld, Dereuddre-Bosquet, Martinon, Pålsson, Zaghloul, Brodin, Sander, Lennox, Behlke, El-Andaloussi, Lehtiö, Lundeberg, LeGrand, Spetz: "Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis." in: Scientific reports, Vol. 8, Issue 1, pp. 15841, (2019) (PubMed).

Zhenjiang, Rao, Luo, Valentini, von Landenberg, Meng, Sinclair, Hoffmann, Karbach, Altmannsberger, Jäger, Peredo, Dodoo, Maeurer: "Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme." in: EBioMedicine, Vol. 33, pp. 49-56, (2018) (PubMed).

Phuah, Wong, Gideon, Maiello, Coleman, Hendricks, Ruden, Cirrincione, Chan, Lin, Flynn: "Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques." in: Infection and immunity, Vol. 84, Issue 5, pp. 1301-1311, (2017) (PubMed).

Min, Wang, Yuan, Kuang, Zhao: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." in: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL6

Gen-ID: 3569

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome