IL-6 Antikörper

Produktnummer ABIN6963871

Dieses Anti-IL-6-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von IL-6 in ELISA und ELISpot. Geeignet für Human und Non-Human Primate. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für IL-6 Antikörper (ABIN6963871)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Human, Non-Human Primate

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist unkonjugiert

Applikation: ELISA, ELISpot

Klon: 13A5

Produktdetails anti-IL-6 Antikörper

Spezifität: Native and recombinant IL-6

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with IL-6 from non-human primates.

Produktmerkmale: This monoclonal antibody enables specific detection of human IL-6 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human IL-6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963871, ABIN7448314 and ABIN6964024 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963872 and ABIN7448315 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-IL-6 Antikörper (ABIN6963871)

Palizgir, Akhtari, Mahmoudi, Mostafaei, Rezaiemanesh, Shahram: "Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with Behcet's disease." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 4, pp. 297-302, (2018) (PubMed).

Sui, Hogg, Wang, Frey, Yu, Xia, Venzon, McKinnon, Smedley, Gathuka, Klinman, Keele, Langermann, Liu, Franchini, Berzofsky: "Vaccine-induced myeloid cell population dampens protective immunity to SIV." in: The Journal of clinical investigation, Vol. 124, Issue 6, pp. 2538-49, (2014) (PubMed).

Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

Feliu, Walter, Montañez, Kunzmann, Hult, Nyström, Malkoch, Fadeel: "Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers." in: Biomaterials, Vol. 33, Issue 7, pp. 1970-81, (2012) (PubMed).

Snyder-Cappione, Tincati, Eccles-James, Cappione, Ndhlovu, Koth, Nixon: "A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-α and MIP1-β, a lack of IL-17, and a Th1-bias in males." in: PLoS ONE, Vol. 5, Issue 11, pp. e15412, (2011) (PubMed).

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL6

Gen-ID: 3569

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome