CD40 Antikörper
Kurzübersicht für CD40 Antikörper (ABIN6961737)
Target
Alle CD40 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
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Isotyp
- IgG1 kappa
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Kommentare
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0.5 mg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C
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Haltbarkeit
- 12 months
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- CD40
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Andere Bezeichnung
- CD40
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Hintergrund
- The G28.5 antibody reacts with human CD40, a 45-48 kDa glycoprotein that is a member of the TNF-receptor superfamily. CD40 is expressed on B cells, follicular dendritic cells, macrophages, endothelial cells, and fibroblasts. CD40 functions as a receptor for CD154 (CD40 ligand) and mediates a wide variety of immune and inflammatory responses including co-stimulation, B cell differentiation, isotype class switching, and germinal center formation.
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Gen-ID
- 958
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Pathways
- NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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