CD40 Antikörper (APC)

Produktnummer ABIN7277985

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD40 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD40 Antikörper (APC) (ABIN7277985)

Target: CD40

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: G28-5

Produktdetails anti-CD40 Antikörper (APC)

Aufreinigung: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: This antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 μLper test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.

Kommentare:

5μl (0.25μg)/test

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C protected from light

Haltbarkeit: 12 months

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund: The G28.5 antibody reacts with human CD40, a 45-48 kDa glycoprotein that is a member of the TNF-receptor superfamily. CD40 is expressed on B cells, follicular dendritic cells, macrophages, endothelial cells, and fibroblasts. CD40 functions as a receptor for CD154 (CD40 ligand) and mediates a wide variety of immune and inflammatory responses including co-stimulation, B cell differentiation, isotype class switching, and germinal center formation.

Gen-ID: 958

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints