CD11b Antikörper

Produktnummer ABIN6942386

Der Kaninchen Monoklonal anti-CD11b Antikörper (Klon 9B3) (ABIN6942386) detektiert spezifisch CD11b in WB, IHC (fro), IHC (p) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD11b Antikörper (ABIN6942386)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Klon: 9B3

Produktdetails anti-CD11b Antikörper

Verwendungszweck: CD11b Monoclonal Antibody

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant Human ITGAM

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(WB(1:1000-2000)), IHC-P(IHC-P(1:200-800)), IHC-F(IHC-F(1:200-800)), IF(IHC-P)(IF(IHC-P)(1:200-800))

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: CD11b

Hintergrund:

Synonyms: Antigen CD11b (p170), CD11 antigen like family member B, CD11 antigen like family member C, Cell surface glycoprotein MAC 1 subunit alpha, CR 3 alpha chain, CR3A, Integrin alpha M, Integrin alpha X, Integrin, alpha M (complement component 3 receptor 3 subunit), Integrin, alpha X (antigen CD11C (p150), alpha polypeptide), Integrin, alpha X (complement component 3 receptor 4 subunit), ITGAM, ITGAX, Leu M5, alpha subunit, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor MO1, Leukocyte adhesion receptor p150,95, Leukocyte surface antigen p150,95, alpha subunit, MAC1A, Macrophage antigen alpha polypeptide, MO1A, Myeloid membrane antigen, alpha subunit, Neutrophil adherence receptor alpha M subunit, p150 95 integrin alpha chain, SLEB6, ITAM_HUMAN, c equivalent, Integrin αM.

Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Gen-ID: 3684

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation