IL-6 Antikörper

Produktnummer ABIN6941475

Der Ratte Monoklonal anti-IL-6 Antikörper (Klon MP5-20F3) (ABIN6941475) detektiert spezifisch IL-6 in FACS, Neut und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für IL-6 Antikörper (ABIN6941475)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Neutralization (Neut), Immunofluorescence (IF)

Klon: MP5-20F3

Produktdetails anti-IL-6 Antikörper

Keine Kreuzreaktivität: Human, Ratte (Rattus)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant Mouse IL-6 protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Mouse heart.

Known Application: Neutralization Studies (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL-6 (Interleukin-6)

Hintergrund: IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.

Molekulargewicht: 21kDa

Gen-ID: 16193

UniProt: P08505

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome