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CD14 Antikörper

CD14 Reaktivität: Human FACS, IF Wirt: Maus Monoclonal LPSR-927 unconjugated

Produktnummer ABIN6936599

Datenblatt (PDF)

Target Alle CD14 Antikörper anzeigen

CD14
Reaktivität
228

38

32

25

24

18

17

15

14

14

13

10

9

9

8

8

8

5

2

2

2

1

1

1
Human
Wirt
202

44

25

3

1
Maus
Passende Sekundärantikörper
Klonalität
230

45
Monoklonal
Konjugat
116

29

21

15

14

8

5

5

5

4

4

4

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD14 Antikörper ist unkonjugiert
Applikation
205

83

57

54

49

44

21

13

12

12

7

6

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Spezifität

Recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

Kreuzreaktivität (Details)

Human.

Aufreinigung

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen

Recombinant human CD14 protein

Klon

LPSR-927

Isotyp

IgG1 kappa

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CD14 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal 1D1F8 unconjugated

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CD14 Reaktivität: Human FACS, WB, IHC, ISt, StM Wirt: Maus Monoclonal LPSR-2385 unconjugated

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CD14 Reaktivität: Human, Non-Human Primate FACS, WB, ELISA, IP Wirt: Maus Monoclonal MEM-18 unconjugated

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CD14 Reaktivität: Human, Non-Human Primate FACS, WB, ELISA, IP, Func Wirt: Maus Monoclonal MEM-18 unconjugated

anti-CD14 (CD14) antibody (Biotin)
CD14 Reaktivität: Human, Non-Human Primate FACS, WB, ELISA, IP Wirt: Maus Monoclonal MEM-18 Biotin

Applikationshinweise

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 cells and human monocytes. Lymph nodes and tonsils.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel

Azide free

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit

24 months
Target

CD14

Andere Bezeichnung

CD14 (CD14 Produkte)

Synonyme

CD14 molecule antikoerper, CD14 antigen antikoerper, CD14 antikoerper, Cd14 antikoerper

Hintergrund

Lipopolysaccharide receptor, LPS-R, LPSR, Mo2, Monocyte Differentiation Antigen 14, Myeloid cell-specific leucine-rich glycoprotein,CD14 (Monocyte / Macrophage Marker)
Cellular localisation: Cell Surface

Molekulargewicht

55kDa

Gen-ID

929, 163867

UniProt

P08571

Pathways

TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades