LRP6 Antikörper (PE)

Produktnummer ABIN681488

Der Kaninchen Polyklonal anti-LRP6 Antikörper wird verwendet zum Nachweis von LRP6 in Proben von Human. Er wurde validiert für IF (p).

Kurzübersicht für LRP6 Antikörper (PE) (ABIN681488)

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP6 Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-LRP6 Antikörper (PE)

Verwendungszweck: LRP6 Polyclonal Antibody, PE Conjugated

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LRP6

Target: LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))

Andere Bezeichnung: LRP6

Hintergrund:

Synonyms: ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6, LRP-5, LR3, LRP7, Low-density lipoprotein receptor-related protein 5.

Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

Molekulargewicht: 177kDa

Gen-ID: 4040

Pathways: WNT Signalweg, Tube Formation