ERK1 Antikörper (pThr202, pThr204) (Biotin)

Produktnummer ABIN6735479

Dieser Maus Monoklonal Antikörper detektiert spezifisch ERK1 in WB, ELISA, IP und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ERK1 Antikörper (pThr202, pThr204) (Biotin) (ABIN6735479)

Target: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERK1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktdetails anti-ERK1 Antikörper (Biotin)

Bindungsspezifität: pThr202, pThr204

Spezifität: Recognizes the FLpTEpYVA motif of activated human ERK1 and ERK2. Requires phosphorylation both at the threonine and the tyrosine site and does not cross-react with the non-phosphorylated form of the protein. Does not cross-react with activated JNK or p38. Species cross-reactivity: mouse, rat, and canine.

Kreuzreaktivität: Hund, Maus, Ratte (Rattus)

Aufreinigung: Gel Filtration Chromatography

Immunogen: Synthetic peptide corresponding to the FLpTEpYVA motif of phosphorylated ERK1/2 (MAPK2/3). Conjugated to KLH.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA (0.05 µg/mL), ICC (1 - 10 µg/mL), IP, WB (0.5 µg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.09% sodium azide, G, sucrose, 40% glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Details zu ERK1

Target: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Andere Bezeichnung: MAPK3 / ERK1

Hintergrund: Standard Gene Symbol: MAPK3, Gene Family: Protein Kinase, Gene Subfamily: MAPK, Synonyms: MAPK3, ERK-1, ERT2, HUMKER1A, HS44KDAP, MAP kinase 1, MAP kinase isoform p44, MAPK 1, MAPK 3, p44, p44MAPK, p44-MAPK, p44ERK1, Insulin-stimulated MAP2 kinase, MAP kinase 3, p44-ERK1, ERK1, PRKM3

Gen-ID: 5595

UniProt: P27361

Pathways: MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteine