Growth Hormone Receptor Antikörper (AA 101-200) (Biotin)
Kurzübersicht für Growth Hormone Receptor Antikörper (AA 101-200) (Biotin) (ABIN671483)
Target
Alle Growth Hormone Receptor (GHR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 101-200
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Kreuzreaktivität
- Human, Maus, Schwein, Ratte, Schaf
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Homologie
- Dog,Cow,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human GHR
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- Growth Hormone Receptor (GHR)
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Andere Bezeichnung
- GHR
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Hintergrund
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Synonyms: GHBP, Growth hormone receptor, GH receptor, Somatotropin receptor, GHR
Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
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Gen-ID
- 2690
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UniProt
- P10912
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Pathways
- NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus
Target
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