CD14 Antikörper (Internal Region)

Produktnummer ABIN6657883

Hersteller Produkt- Nr.: 600-401-r04

Der Kaninchen Polyklonal anti-CD14 Antikörper wird verwendet zum Nachweis von CD14 in Proben von Maus. Er wurde validiert für WB.

Kurzübersicht für CD14 Antikörper (Internal Region) (ABIN6657883)

Target: CD14

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD14 Antikörper

Bindungsspezifität: Internal Region

Hersteller Produkt- Nr.: 600-401-r04

Hersteller: Rockland

Verwendungszweck: CD14 Antibody

Kreuzreaktivität (Details): Anti-CD14 antibody is directed against mouse CD14 protein.

Aufreinigung: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: CD14 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse CD14.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 0.5 μg/mL

Kommentare:

Anti-CD14 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~39.2 kDa corresponding to the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund:

Synonyms: Myeloid cell-specific leucine-rich glycoprotein,CD_antigen=CD14,

Background: CD14, Cluster of differentiation 14, single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. By in situ hybridization and study of somatic cell hybrid DNA that the gene is located at bands 5q23-q31. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns. This antibody is suitable for researchers interested in stem cell research.

Gene Name: CD14

Gen-ID: 12475

NCBI Accession: NP_033971

UniProt: P10810

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades