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VAV1 Antikörper (AA 437-466)

VAV1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB33825 unconjugated
Produktnummer ABIN657774
  • Target Alle VAV1 Antikörper anzeigen
    VAV1 (Vav 1 Oncogene (VAV1))
    Bindungsspezifität
    • 15
    • 11
    • 10
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 437-466
    Reaktivität
    • 69
    • 39
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 67
    • 4
    Kaninchen
    Klonalität
    • 67
    • 4
    Polyklonal
    Konjugat
    • 40
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser VAV1 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 34
    • 12
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This VAV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human VAV1.
    Klon
    RB33825
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product VAV1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    VAV1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    VAV1 (Vav 1 Oncogene (VAV1))
    Andere Bezeichnung
    VAV1 (VAV1 Produkte)
    Synonyme
    VAV antikoerper, Vav antikoerper, vav-T antikoerper, vav guanine nucleotide exchange factor 1 antikoerper, vav 1 oncogene antikoerper, vav guanine nucleotide exchange factor 1 L homeolog antikoerper, VAV1 antikoerper, Vav1 antikoerper, vav1.L antikoerper
    Hintergrund
    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
    Molekulargewicht
    98314
    Gen-ID
    7409
    NCBI Accession
    NP_001245136, NP_005419
    UniProt
    P15498
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, BCR Signaling
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