IRAK4 Antikörper
Kurzübersicht für IRAK4 Antikörper (ABIN6570285)
Target
Alle IRAK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human IRAK4
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Andere Bezeichnung
- IRAK4
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Hintergrund
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Synonyms: IL-1 receptor-associated kinase 4,Interleukin 1 receptor associated kinase 4 mutant form 1,Interleukin-1 receptor-associated kinase 4,Interleukin1 receptor associated kinase 4,IPD1,IRAK 4,IRAK-4,IRAK4,IRAK4 mutated form 1,IRAK4,LOC 51135,NY REN 64,NY REN 64 antigen,NY-REN-64,REN64,Renal carcinoma antigen NY-REN-64
Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
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Observed_MW: 55kDa
Calculated_MW: 37kDa/51kDa
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Gen-ID
- 51135
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UniProt
- Q9NWZ3
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Pathways
- NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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