IRAK4 Antikörper (N-Term)

Produktnummer ABIN656802

Dieses Anti-IRAK4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IRAK4 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für IRAK4 Antikörper (N-Term) (ABIN656802)

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB33094

Produktdetails anti-IRAK4 Antikörper

Bindungsspezifität: AA 25-52, N-Term

Homologie: B, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IRAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human IRAK4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: IRAK4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-IRAK4 Antikörper (ABIN656802)

Ren, Sun, Deng, Zhang, Wu, Wei, Mani, Dou, Wang: "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015) (PubMed).

Details zu IRAK4

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Andere Bezeichnung: IRAK4

Hintergrund: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 51530

Gen-ID: 51135

NCBI Accession: NP_001107654, NP_001138728, NP_001138729, NP_001138730, NP_057207

UniProt: Q9NWZ3

Pathways: NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades