PPP1CA Antikörper

Produktnummer ABIN5963938

Dieses Anti-PPP1CA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PPP1CA in WB und IHC. Geeignet für Human und Maus.

Kurzübersicht für PPP1CA Antikörper (ABIN5963938)

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1CA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PPP1CA Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PPP1CA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPP1CA

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Andere Bezeichnung: PPP1CA

Hintergrund:

Synonyms: Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit,Catalytic subunit,EC 3.1.3.16,MGC15877,MGC1674,PP 1A,PP-1A,PP1A,PP1A,PP1alpha,PP2C ALPHA,PP2CA,Ppp1ca,Protein Phosphatase 2C Alpha Isoform,Serine threonine protein phosphatase PP1 alpha catalytic subunit,Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1,Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 38kDa

Calculated_MW: 32kDa/37kDa/38kDa

Gen-ID: 5499

UniProt: P62136

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism