Cadherin 4 Antikörper
Kurzübersicht für Cadherin 4 Antikörper (ABIN6566983)
Target
Alle Cadherin 4 (CDH4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human CDH4
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cadherin 4 (CDH4)
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Andere Bezeichnung
- R-Cadherin
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Hintergrund
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Synonyms: CADH4,Cadherin 4,Cadherin-4,cdh4,R CAD,R-CAD,R-cadherin,Retinal cadherin
Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
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Observed_MW: 100kDa
Calculated_MW: 92kDa/100kDa
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Gen-ID
- 1002
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UniProt
- P55283
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Pathways
- Cell-Cell Junction Organization, Regulation of Cell Size
Target
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