BRAF Antikörper
-
- Target Alle BRAF Antikörper anzeigen
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser BRAF Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human BRAF
- Isotyp
- IgG
- Top Product
- Discover our top product BRAF Primärantikörper
-
-
- Applikationshinweise
- WB 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
- Andere Bezeichnung
- BRAF (BRAF Produkte)
- Hintergrund
-
Synonyms: FLJ95109,94 kDa B raf protein,B raf 1,B Raf proto oncogene serine threonine protein kinase,B Raf proto oncogene,serine/threonine kinase,B RAF1,B-Raf proto-oncogene serine/threonine-protein kinase (p94),BRAF 1,BRAF,BRAF,BRAF1,cRmil,MGC126806,MGC138284,Murine sarcoma viral (v-raf) oncogene homolog B1,Murine sarcoma viral v raf oncogene homolog B1,NS7,Oncogen BRAF,oncogene BRAF1,p94,Proto-oncogene B-Raf,Proto-oncogene c-Rmil,RAFB 1,RAFB1,RMIL,Serine/threonine-protein kinase B-raf,v raf murine sarcoma viral oncogene homolog B,v raf murine sarcoma viral oncogene homolog B1,v-Raf murine sarcoma viral oncogene homolog B1
Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
- Molekulargewicht
-
Observed_MW: 98kDa
Calculated_MW: 84kDa
- Gen-ID
- 673
- UniProt
- P15056
- Pathways
- MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie
-