IRF9 Antikörper (AA 75-104)
-
- Target Alle IRF9 Antikörper anzeigen
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
-
Bindungsspezifität
- AA 75-104
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IRF9 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids of human IRF9.
- Klon
- RB19229
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IRF9 Primärantikörper
-
-
- Applikationshinweise
- IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
-
- Target
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Andere Bezeichnung
- IRF9 (IRF9 Produkte)
- Hintergrund
- IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- Molekulargewicht
- 43696
- Gen-ID
- 10379
- NCBI Accession
- NP_006075
- UniProt
- Q00978
- Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
-