IRF9 Antikörper (N-Term)

Produktnummer ABIN2777226

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-IRF9 Antikörper (ABIN2777226) detektiert spezifisch IRF9 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für IRF9 Antikörper (N-Term) (ABIN2777226)

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-IRF9 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ISGF3G Antibody - N-terminal region

Sequenz: PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ISGF3G. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ISGF3G

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103270

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-IRF9 Antikörper (ABIN2777226)

Bidwell, Slaney, Withana, Forster, Cao, Loi, Andrews, Mikeska, Mangan, Samarajiwa, de Weerd, Gould, Argani, Möller, Smyth, Anderson, Hertzog, Parker: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." in: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).

Schumacher, Lau, Johnson: "Structural basis of core promoter recognition in a primitive eukaryote." in: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).

Details zu IRF9

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Andere Bezeichnung: ISGF3G

Hintergrund:

Background Information: ISGF3G functions to recruit RNA polymerase II to the promoter of interferon-stimulated genes and requires histone deacetylases. Defects in ISGF3 can cause resistance to IFN-.(2a) treatment.

Gene Name: Interferon regulatory factor 9

Alternative Symbols: p48, IRF-9, ISGF3, ISGF3G

Protein Name: Interferon regulatory factor 9

Molekulargewicht: 44 kDa

Gen-ID: 10379

NCBI Accession: NP_006075

UniProt: Q00978

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C