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IRF9 Antikörper (N-Term)

IRF9 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777226
  • Target Alle IRF9 Antikörper anzeigen
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 49
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 43
    • 7
    • 1
    Kaninchen
    Klonalität
    • 45
    • 5
    Polyklonal
    Konjugat
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF9 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 15
    • 13
    • 13
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ISGF3G. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ISGF3G
    Top Product
    Discover our top product IRF9 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 393 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bidwell, Slaney, Withana, Forster, Cao, Loi, Andrews, Mikeska, Mangan, Samarajiwa, de Weerd, Gould, Argani, Möller, Smyth, Anderson, Hertzog, Parker: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." in: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).

    Schumacher, Lau, Johnson: "Structural basis of core promoter recognition in a primitive eukaryote." in: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).

  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Andere Bezeichnung
    ISGF3G (IRF9 Produkte)
    Synonyme
    IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper
    Hintergrund
    ISGF3G functions to recruit RNA polymerase II to the promoter of interferon-stimulated genes and requires histone deacetylases. Defects in ISGF3 can cause resistance to IFN-.(2a) treatment.
    Alias Symbols: IRF-9, ISGF3, ISGF3G, p48
    Protein Interaction Partner: S100A13, MYO1F, TOP1, IRF1, IRF2BP1, DNMT3A, ELAVL1, STAT2, IFNAR2, CREBBP, DACH2, DMRTC2, TLX3, VENTX, ARID3B, NR2E3, POU2F1, HOXC9, TLX2, STAT1, IFNA1, RELA, NFKB1,
    Protein Size: 393
    Molekulargewicht
    44 kDa
    Gen-ID
    10379
    NCBI Accession
    NM_006084, NP_006075
    UniProt
    Q00978
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
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