MDM2 Antikörper
Kurzübersicht für MDM2 Antikörper (ABIN643835)
Target
Alle MDM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse Anti-Human MDM2
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Spezifität
- DS-MB-01878 recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer. This product has been reported for use in Western blotting. This product reacts with: Mouse. Antibody reactivity and working conditions may vary between species.
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Produktmerkmale
- Transcription and its regulation
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Aufreinigung
- Purified
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Immunogen
- Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2.
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Isotyp
- IgG1
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Applikationshinweise
- Immunohistology - Frozen, Immunohistology - Paraffin, Immunohistology - Resin
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline pH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
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Andere Bezeichnung
- MDM2
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Autophagie, Ubiquitin Proteasome Pathway
Target
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