TNF alpha Antikörper

Produktnummer ABIN639404

Der Ratte Anti-TNF alpha Antikörper wurde für ELISA, FACS und IHC (fro) validiert. Er ist geeignet, TNF alpha in Proben von Maus zu detektieren.

Kurzübersicht für TNF alpha Antikörper (ABIN639404)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Maus

Wirt: Ratte

Konjugat: Dieser TNF alpha Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TNF alpha Antikörper

Spezifität: DS-MB-02427 is specific for mouse tumor necrosis factor alpha (TNF alpha), a 17 KDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a 26KDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immuno-regulatory role. DS-MB-02427 is reported to neutralize the effects of mouse TNF alpha (4,5).

Kreuzreaktivität: Ratte (Rattus)

Produktmerkmale: Rat Anti-Mouse Tumor Necrosis Factor alpha (TNF-alpha)

Aufreinigung: Purified

Immunogen: Recombinant murine TNF alpha expressed in E. coli

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: Tumor Necrosis Factor alpha (TNF-alpha)

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome