TNF alpha Antikörper

Produktnummer ABIN639286

Dieser Maus Antikörper erkennt spezifisch TNF alpha in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Rind (Kuh).

Kurzübersicht für TNF alpha Antikörper (ABIN639286)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Rind (Kuh)

Wirt: Maus

Konjugat: Dieser TNF alpha Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Produktdetails anti-TNF alpha Antikörper

Spezifität: This product recognizes bovine TNF alpha, a 17.5kDa cytokine, expressed by many different stimulated cell types including monocytes, macrophages, endothelial cells, fibroblasts and both T and B-lymphocytes. The production of TNF alpha is induced by a variety of factors, dependant upon cell type and includes bacterial toxins, IL-1, PDGF, IFN-beta, NGF, Oncostatin M and viral infections. The presence of TNF alpha is responsible for diverse immunomodulatory, anti-tumour and toxic effects and under certain conditions is also capable of self-stimulation and inhibition.

Kreuzreaktivität: Schaf

Produktmerkmale: Mouse Anti-Bovine Tumor Necrosis Factor alpha (TNF-alpha)

Aufreinigung: Purified

Immunogen: Recombinant bovine TNF alpha

Isotyp: IgG2b

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: Tumor Necrosis Factor alpha (TNF-alpha)

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome