Patched 1 Antikörper
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- Target Alle Patched 1 (PTCH1) Antikörper anzeigen
- Patched 1 (PTCH1)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Patched 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purified
- Immunogen
- PTCH1 antibody was raised using a synthetic peptide corresponding to a region with amino acids TILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAM
- Top Product
- Discover our top product PTCH1 Primärantikörper
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- Applikationshinweise
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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PTCH1 Blocking Peptide, catalog no. 33R-9121, is also available for use as a blocking control in assays to test for specificity of this PTCH1 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PTCH1 antibody in PBS
- Konzentration
- Lot specific
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- Patched 1 (PTCH1)
- Andere Bezeichnung
- PTCH1 (PTCH1 Produkte)
- Hintergrund
- PTCH1 is a member of the patched gene family. The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. It functions as a tumor suppressor. Mutations of its gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
- Molekulargewicht
- 37 kDa (MW of target protein)
- Pathways
- Hedgehog Signalweg, Carbohydrate Homeostasis, Tube Formation
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