Patched 1 Produkte
(Patched 1 (PTCH1))
Kategorien
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008].
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Ausgewählte Patched 1 Kategorien
Patched 1 Antikörper
High quality antibodies with extensive validation data.
Patched 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Patched 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Patched 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, IHC, IF
Validierungen
- (2)
- (7)
Kat. Nr.
ABIN185521
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7255007
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (8)
Kat. Nr.
ABIN3015343
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Patched 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958422
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381402
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Chicken
Analytical Method
Validierungen
Kat. Nr.
ABIN1152106
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Patched 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN7199704
Menge
2 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1316702
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3086680
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Patched 1 Produkten
: "Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo." in: International journal of cancer, Vol. 143, Issue 1, pp. 199-211, (2019) (PubMed).: "Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling." in: Experimental cell research, Vol. 371, Issue 2, pp. 417-425, (2018) (PubMed).
: "Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment." in: Biology of reproduction, Vol. 96, Issue 2, pp. 313-326, (2017) (PubMed).
: "Knockdown of HIF-1α inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway." in: Life sciences, Vol. 191, pp. 82-89, (2017) (PubMed).
: "Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate." in: PLoS genetics, Vol. 12, Issue 10, pp. e1006352, (2016) (PubMed).
: "Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth In Vivo by Affecting Stroma." in: Molecular cancer therapeutics, Vol. 15, Issue 5, pp. 1095-105, (2016) (PubMed).
: "Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen." in: Experimental neurology, Vol. 271, pp. 493-505, (2015) (PubMed).
: "Developmental Status: Impact of Short-Term Ischemia on Follicular Survival of Whole Ovarian Transplantation in a Rabbit Model." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135049, (2015) (PubMed).
: "Expression of Hedgehog ligand and signal transduction components in mutually distinct isocitrate dehydrogenase mutant glioma cells supports a role for paracrine signaling." in: Journal of neuro-oncology, Vol. 119, Issue 2, pp. 243-51, (2014) (PubMed).
: "High expression of Sonic Hedgehog signaling pathway genes indicates a risk of recurrence of breast carcinoma." in: OncoTargets and therapy, Vol. 7, pp. 79-86, (2014) (PubMed).
Synonyme und alternative Namen zu Patched 1
patched 1 (PTCH1), patched 1 (ptch1), patched 1 (Ptch1), patched 1 L homeolog (ptch1.L), Protein patched homolog 1 (ptc-1), A230106A15Rik, BCNS, HPE7, lep, mes, NBCCS, patched, patched1, PTC, Ptc, Ptc-1, PTC1, ptc1, Ptc1, ptc2, PTCH, Ptch, Ptch2, PTCH11, XPtc1Bezeichner auf Proteinebene für Patched 1
- PTCH protein +12b
- PTCH protein +4'
- PTCH protein -10
- PTCH protein -3,4,5
- protein patched homolog 1
- leprechaun
- patched 2
- patched homolog 2
- patched homolog 1
- patched-1
- patched 1
- patched-like
- protein patched homolog 1-like
- Patched 1
- Ptch1 protein +12b
- mesenchymal dysplasia
- PTC1
- patched protein
- patched-like protein
- LOW QUALITY PROTEIN: protein patched homolog 1
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