TNF alpha Antikörper (Biotin)

Produktnummer ABIN6297805

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TNF alpha in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TNF alpha Antikörper (Biotin) (ABIN6297805)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Klon: 5H4-F10-E11

Produktdetails anti-TNF alpha Antikörper (Biotin)

Verwendungszweck: Mouse anti-Human TNF alpha Biotinylated Antibody

Immunogen: This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: -20°C

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNF alpha

Hintergrund:

Target Description: TNF alpha is an  adipokine  involved in systemic  inflammation  and is a member of a group of cytokines that stimulate the  acute phase reaction. It is produced chiefly by activated  macrophages  (M1), although it can be produced by many other cell types such asCD4+ lymphocytes,  NK cells, neutrophils, mast cells, eosinophils, and neurons.

UniProt: P78536

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome