IGF1 Antikörper

Produktnummer ABIN6296855

Der Maus Monoklonal Anti-IGF1-Antikörper wurde für IF, FACS, AcA, in vitro, Func und Inhibition validiert. Er ist geeignet, IGF1 in Proben von Human, Maus, Ratte und Kaninchen zu detektieren.

Kurzübersicht für IGF1 Antikörper (ABIN6296855)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Activity Assay (AcA), In vitro Assay (in vitro), Functional Studies (Func), Blocking Antibody (Inhibition)

Produktdetails anti-IGF1 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Rabbit IGF1 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic (Secreted)

Aufreinigung: Purified human IGF1 protein was used as the immunogen for this antibody.

Immunogen: Purified human IGF1 protein was used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
Functional Activity: In vitro inhibition of IGF1 Activity, order BSA/azide free format

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Andere Bezeichnung: Insulin-like growth factor I

Hintergrund:

Target Description: This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Gene Symbol: IGF1///IBP1

Gen-ID: 3479

UniProt: P05019

Pathways: RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation