CD36 Antikörper

Produktnummer ABIN6296379

Dieses Anti-CD36-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD36 in FACS, IF, ELISA und Func. Geeignet für Human.

Kurzübersicht für CD36 Antikörper (ABIN6296379)

Target: CD36

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD36 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Functional Studies (Func)

Produktdetails anti-CD36 Antikörper

Verwendungszweck: Mouse anti-Human CD36 Antibody [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: Human CD36 from platelets was used as the immunogen for the CD36 antibody.

Immunogen: Human CD36 from platelets was used as the immunogen for the CD36 antibody.

Anwendungsinformationen

Applikationshinweise: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL,ELISA: order the BSA free format

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD36

Target: CD36

Andere Bezeichnung: Platelet glycoprotein 4

Hintergrund:

Target Description: Recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4 % of Japanese and East Asia population lack CD36.

Gene Symbol: CD36///GP3B///GP4

Gen-ID: 948

UniProt: P16671

Pathways: TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteine