IGF1 Antikörper

Produktnummer ABIN6296313

Dieses Anti-IGF1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IGF1 in IF, FACS, Neut, AcA, in vitro und Func. Geeignet für Human, Maus, Ratte und Kaninchen.

Kurzübersicht für IGF1 Antikörper (ABIN6296313)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Neutralization (Neut), Activity Assay (AcA), In vitro Assay (in vitro), Functional Studies (Func)

Produktdetails anti-IGF1 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Rabbit IGF-1 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic (secreted)

Aufreinigung: Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

Immunogen: Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Functional Activity: In-vitro neutralization of biological activity of IGF-1 (Order SAF formulation)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Andere Bezeichnung: Insulin-like growth factor I

Hintergrund:

Target Description: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Gene Symbol: IGF1///IBP1

Gen-ID: 3479

UniProt: P05019

Pathways: RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation