TRADD Antikörper
Kurzübersicht für TRADD Antikörper (ABIN6265700)
Target
Alle TRADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- TRADD antibody detects endogenous levels of total TRADD
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Kreuzreaktivität
- Human, Affe, Maus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human TRADD
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Isotyp
- IgG
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anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-312) antibody
TRADD Reaktivität: Human WB, IHC, ELISA, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 111-230) antibodyTRADD Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibodyTRADD Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB18788 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) antibodyTRADD Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-177) antibodyTRADD Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 3A1E8 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 133-159), (Middle Region) antibodyTRADD Reaktivität: Human WB, IF, IHC (p), FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 61-297) antibodyTRADD Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD Reaktivität: Human, Maus, Affe WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibodyTRADD Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB2230 unconjugated Recombinant Antibody
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Applikationshinweise
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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Andere Bezeichnung
- TRADD
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Hintergrund
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Description: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Gene: TRADD
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Molekulargewicht
- 34kDa
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Gen-ID
- 8717
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UniProt
- Q15628
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Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C
Target
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