Cyclin A Antikörper (C-Term)

Produktnummer ABIN6261138

Es sind 4+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-Cyclin A Antikörper wird verwendet zum Nachweis von Cyclin A in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, IHC, IF und ICC.

Kurzübersicht für Cyclin A Antikörper (C-Term) (ABIN6261138)

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Cyclin A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Cyclin A Antibody

Spezifität: Cyclin A antibody detects endogenous levels of total Cyclin A

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cyclin A, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC: 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-Cyclin A Antikörper (ABIN6261138)

Liao, Xiao, Chen, Zhang, Chen, Long, Gao, He, Ge, Yi, Wu, Li, Zhou: "The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer." in: International journal of oncology, Vol. 51, Issue 5, pp. 1497-1507, (2018) (PubMed).

Huang, Song, Tao, Shao, Zeng, Xu, Qi, Sun: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." in: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).

Liao, Xiao, Chen, Zhang, Chen, Long, Gao, Zhu, He, Peng, Xiong, Zeng, Li, Zhou, Li, Ma, Wu, Xiang, Li, Zhou: "CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions." in: Molecular carcinogenesis, Vol. 56, Issue 10, pp. 2245-2257, (2017) (PubMed).

Chen, Suo, Cheng, Zheng, Xu: "Vascular endothelial growth factor C enhances cervical cancer migration and invasion via activation of focal adhesion kinase." in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, Vol. 29, Issue 1, pp. 20-4, (2013) (PubMed).

Details zu Cyclin A

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Andere Bezeichnung: Cyclin A

Hintergrund:

Description: May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.

Gene: CCNA1

Molekulargewicht: 53kDa

Gen-ID: 8900

UniProt: P78396

Pathways: PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA