Caspase 9 Antikörper (pThr125)
Kurzübersicht für Caspase 9 Antikörper (pThr125) (ABIN6256471)
Target
Alle Caspase 9 (CASP9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- pThr125
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                                            Spezifität
- Phospho-Caspase 9 (Thr125) Antibody detects endogenous levels of Caspase 9 only when phosphorylated at Threonine 125.
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                                            Homologie
- Pig,Bovine,Horse,Sheep
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                                            Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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                                            Immunogen
- A synthesized peptide derived from human Caspase 9 around the phosphorylation site of Thr125.
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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                                            Haltbarkeit
- 12 months
 
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    - Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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                                            Andere Bezeichnung
- CASP9
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                                            Hintergrund
- 
                        Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Gene: CASP9 
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                                            Molekulargewicht
- 47kDa
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                                            Gen-ID
- 842
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                                            UniProt
- P55211
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                                            Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
 Target
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