FADD Antikörper (pSer194)
Kurzübersicht für FADD Antikörper (pSer194) (ABIN6255063)
Target
Alle FADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer194
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Verwendungszweck
- Phospho-FADD (Ser194) Antibody
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Spezifität
- Phospho-FADD (Ser194) Antibody detects endogenous levels of FADD only when phosphorylated at Ser194.
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Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human FADD around the phosphorylation site of Ser194.
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Isotyp
- IgG
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibody
FADD Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibodyFADD Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 20-150) antibodyFADD Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5A6A2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD Reaktivität: Maus WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reaktivität: Human WB, IHC, ELISA, IF, ICC Wirt: Maus Monoclonal J1D2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 106-135) antibodyFADD Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40884 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (C-Term) antibodyFADD Reaktivität: Human, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Andere Bezeichnung
- FADD
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Hintergrund
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Description: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Gene: FADD
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Molekulargewicht
- 23kDa
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Gen-ID
- 8772
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UniProt
- Q13158
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Pathways
- Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Target
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