TNF alpha Antikörper

Produktnummer ABIN6254207

Der Ziege Polyklonal anti-TNF alpha Antikörper wird verwendet zum Nachweis von TNF alpha in Proben von Human, Maus, Ratte, Kaninchen, Schwein, Hund, Rind (Kuh), Schaf, Affe, Cat, Pferd, Meerschweinchen, Ziege, Huhn, Hamster, Avian und Esel. Er wurde validiert für WB.

Kurzübersicht für TNF alpha Antikörper (ABIN6254207)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Hund, Rind (Kuh), Schaf, Affe, Cat, Pferd, Meerschweinchen, Ziege, Huhn, Hamster, Avian, Esel

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TNF alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TNF alpha Antikörper

Verwendungszweck: anti-TNF alpha

Sequenz: MSTESMIRDV ELAEEALPKK TGGPQGSRRC LFLSLFSFLI VAGATTLFCL LHFGVIGPQR EEFPRDLSLI SPLAQAVRSS SRTPSDKPVA HVVANPQAEG QLQWLNRRAN ALLANGVELR DNQLVVPSEG LYLIYSQVLF KGQGCPSTHV LLTHTISRIA VSYQTKVNLL SAIKSPCQRE TPEGAEAKPW YEPIYLGGVF QLEKGDRLSA EINRPDYLDF AESGQVYFGI IAL

Spezifität: Detects a band of approximately 17 kDa using Raw264.7 cell line by Western blot.

Produktmerkmale: Tumor necrosis factor

Aufreinigung: Epitope affinity purified

Immunogen: Purified recombinant human TNF-_ produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:2,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNF alpha

Hintergrund:

Goat polyclonal antibody to TNF alpha. TNF-α is produced by a variety of immune cells including NK cells, B cells, T cells and macrophages. It is multifunctional proinflammatory cytokine that belongs to the tumour necrosis factor (TNF) superfamily. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is involved in the regulation of several processes including lipid metabolism cell differentiation and proliferation, coagulation and apoptosis. It has been implicated in a variety of diseases, including cancer and autoimmune diseases.

APC1, cachectin, tumor necrosis factor ligand superfamily member 2, macrophage-derived TNF, TNF-a, TNF monocyte-derived, tumor necrosis factor-alpha antibody.

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome