CD40 Antikörper
Kurzübersicht für CD40 Antikörper (ABIN6253105)
Target
Alle CD40 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD40 Unconjugated Antibody
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Produktmerkmale
- The clone G28-5 is specific for CD40 B cell surface antigen. It is a 48 kD type I glycoprotein and a member of the tumor necrosis factor receptor superfamily. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4+ T cells. The CD40 on B cells and CD40L (CD154) on activated helper T cells are co-stimulatory molecules whose interaction is required for the proliferation and immunoglobulin (Ig) class switching of antigen-activated B cells.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Human tonsillar lymphocytes
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- CD40
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Andere Bezeichnung
- CD40
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UniProt
- P25942
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Pathways
- NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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