CD14 Antikörper
Kurzübersicht für CD14 Antikörper (ABIN6253091)
Target
Alle CD14 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD14 Unconjugated Antibody
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Produktmerkmale
- The clone M5E2, a mouse monoclonal antibody, specifically recognizes a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The expression of CD14 is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. M5E2 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes. M5E2 has crossreactivity with various species including non-human rhesus macaques.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Full-length human CD14 protein
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- CD14
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Andere Bezeichnung
- CD14
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UniProt
- P08571
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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