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DIABLO Antikörper (C-Term)

Name: DIABLO Antikörper (C-Term)
SKU: ABIN6243156
Price: 434.77 EUR
Availability: InStock

Der Kaninchen Polyklonal Anti-DIABLO-Antikörper wurde für WB, IHC (p) und FACS validiert. Er ist geeignet, DIABLO in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Western blot analysis of SC Antibody (C-term) (ABIN6243156 and ABIN6578976) in T47D cell line lysates (35 μg/lane). (DIABLO Antikörper (C-Term))

SC Antibody (C-term) (ABIN6243156 and ABIN6578976) flow cytometric analysis of MDA-M cells (bottom histogram) compared to a negative control cell (top histogram). (DIABLO Antikörper (C-Term))

FACS

All lanes : Anti-SC Antibody (C-term) at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. (DIABLO Antikörper (C-Term))

Forlin-fixed and paraffin-embedded hun testis tissue reacted with SC Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (DIABLO Antikörper (C-Term))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN6243156

Kurzübersicht für DIABLO Antikörper (C-Term) (ABIN6243156)

Target

Alle DIABLO Antikörper anzeigen

DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser DIABLO Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon

RB20755

Bindungsspezifität
10

5

4

4

3

3

2

1

1

1

1

1
AA 211-239, C-Term

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This SMAC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the C-terminal region of human SMAC.

Isotyp

Ig Fraction
anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-232) antibody
DIABLO Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 131-239) antibody
DIABLO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 56-239) antibody
DIABLO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 168-236) antibody
DIABLO Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibody
DIABLO Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibody
DIABLO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239) antibody
DIABLO Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 199-212) antibody
DIABLO Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibody
DIABLO Reaktivität: Human, Rind (Kuh), Pferd WB Wirt: Kaninchen Polyclonal unconjugated

anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 1-239) antibody
DIABLO Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Abulwerdi, Liao, Liu, Azmi, Aboukameel, Mady, Gulappa, Cierpicki, Owens, Zhang, Sun, Stuckey, Mohammad, Nikolovska-Coleska: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).
Target

DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Andere Bezeichnung

SMAC

Hintergrund

SMAC is an inhibitor of apoptosis protein (IAP)-binding protein. This mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs.

Molekulargewicht

27131

NCBI Accession

NP_001265231, NP_001265232, NP_001265233, NP_001265271, NP_063940, NP_620308

UniProt

Q9NR28

Pathways

Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity