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TNF alpha Antikörper
TNF alpha
Reaktivität: Human
WB, Func, EIA
Wirt: Maus
Monoclonal
MAb1
unconjugated
Produktdetails anti-TNF alpha Antikörper
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Target
Alle TNF alpha Antikörper anzeigen
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Reaktivität
Alle Reaktivitäten für TNF alpha Antikörper
Human
Wirt
Alle Wirte für TNF alpha Antikörper
Maus
Klonalität
Alle Klonalitäten für TNF alpha Antikörper
Monoklonal
Konjugat
Alle Konjugate für TNF alpha Antikörper
Dieser TNF alpha Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNF alpha Antikörper
Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
Spezifität
This antibody recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
Aufreinigung
Affinity Chromatography
Immunogen
Human TNF
Klon
MAb1
Isotyp
IgG1
Top Product
Discover our top product TNF alpha Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS, pH 7.4, 0.09 % Sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Details zu TNF alpha
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Target
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Andere Bezeichnung
Tumor Necrosis Factor (TNF-Alpha) (TNF alpha Produkte )
Synonyme
DIF antikoerper, TNF-alpha antikoerper, TNFA antikoerper, TNFSF2 antikoerper, RATTNF antikoerper, Tnfa antikoerper, tnf antikoerper, TNF-a antikoerper, TNFalpha antikoerper, Tnfsf1a antikoerper, TNFa antikoerper, cTNF antikoerper, Tnf-alpha antikoerper, tnfa-like antikoerper, TNF-ALPHA antikoerper, dif antikoerper, tnfa antikoerper, xtnf antikoerper, tnfsf2 antikoerper, tnf-alpha antikoerper, Cachectin antikoerper, tumor necrosis factor antikoerper, tumor necrosis factor b (TNF superfamily, member 2) antikoerper, tumor necrosis factor alpha antikoerper, tumor necrosis factor a (TNF superfamily, member 2) antikoerper, TNF antikoerper, Tnf antikoerper, tnf antikoerper, tnfb antikoerper, tnf-alpha antikoerper, LOC103694380 antikoerper, tnfa antikoerper
Hintergrund
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
Gen-ID
7124
NCBI Accession
NP_000585
UniProt
P01375
Pathways
NF-kappaB Signalweg , Apoptose , Caspase Kaskade in der Apoptose , TLR Signalweg , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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