CTLA4 Antikörper (AA 49-223)

Produktnummer ABIN6139198

Der Kaninchen Polyklonal anti-CTLA4 Antikörper wird verwendet zum Nachweis von CTLA4 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CTLA4 Antikörper (AA 49-223) (ABIN6139198)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CTLA4 Antikörper

Bindungsspezifität: AA 49-223

Sequenz: SSRGIASFVC EYASPGKATE VRVTVLRQAD SQVTEVCAAT YMMGNELTFL DDSICTGTSS GNQVNLTIQG LRAMDTGLYI CKVELMYPPP YYLGIGNGTQ IYVIDPEPCP DSDFLLWILA AVSSGLFFYS FLLTAVSLSK MLKKRSPLTT GVYVKMPPTE PECEKQFQPY FIPIN

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 49-223 of human CTLA4 (NP_005205.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CTLA4

Hintergrund: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.,CTLA4,ALPS5,CD,CD152,CELIAC3,CTLA-4,GRD4,GSE,IDDM12,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CTLA4

Molekulargewicht: 6 kDa/8 kDa/19 kDa/24 kDa

Gen-ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints