Cadherin 4 Antikörper (AA 757-916)

Produktnummer ABIN6138295

Der Kaninchen Polyklonal Anti-Cadherin 4-Antikörper wurde für WB validiert. Er ist geeignet, Cadherin 4 in Proben von Human zu detektieren.

Kurzübersicht für Cadherin 4 Antikörper (AA 757-916) (ABIN6138295)

Target: Cadherin 4 (CDH4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Cadherin 4 Antikörper

Bindungsspezifität: AA 757-916

Sequenz: KRREKERHTK QLLIDPEDDV RDNILKYDEE GGGEEDQDYD LSQLQQPEAM GHVPSKAPGV RRVDERPVGA EPQYPIRPMV PHPGDIGDFI NEGLRAADND PTAPPYDSLL VFDYEGSGST AGSVSSLNSS SSGDQDYDYL NDWGPRFKKL ADMYGGGEED

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 757-916 of human CDH4 (NP_001785.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cadherin 4

Target: Cadherin 4 (CDH4)

Andere Bezeichnung: CDH4

Hintergrund: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.,CDH4,CAD4,R-CAD,RCAD,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,CDH4

Molekulargewicht: 92 kDa/100 kDa

Gen-ID: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size