MAPK14 Antikörper (Thr180, Tyr182)

Produktnummer ABIN5955633

Der Kaninchen Polyklonal anti-MAPK14 Antikörper wird verwendet zum Nachweis von MAPK14 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für MAPK14 Antikörper (Thr180, Tyr182) (ABIN5955633)

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MAPK14 Antikörper

Bindungsspezifität: Thr180, Tyr182

Spezifität: CSAID Binding Protein 1,CSAID binding protein,CSAID-binding protein,Csaids binding protein,CSBP 1,CSBP 2,CSBP,CSBP1,CSBP2,CSPB1,Cytokine suppressive anti-inflammatory drug-binding protein,EXIP,MAP kinase 14,MAP kinase MXI2,MAP kinase p38 alpha,MAPK 14,MAPK14,MAX interacting protein 2,MAX-interacting protein 2,Mitogen Activated Protein Kinase 14,Mitogen activated protein kinase p38 alpha,Mitogen-activated protein kinase 14,Mitogen-activated protein kinase p38 alpha,MK14,Mxi 2,MXI2,p38 ALPHA,p38,p38 MAP kinase,p38 MAPK,p38 mitogen activated protein kinase,p38ALPHA,p38alpha Exip,PRKM14,PRKM15,RK,SAPK2A

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human p38 around the non-phosphorylation site of Thr180/Tyr182.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAPK14

Target: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Andere Bezeichnung: P38

Hintergrund: Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.

Molekulargewicht: 41kDa

Gen-ID: 1432

UniProt: Q16539

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine