JAK2 Antikörper (AA 1014-1132)
Kurzübersicht für JAK2 Antikörper (AA 1014-1132) (ABIN5776198)
Target
Alle JAK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1014-1132
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Immunogen
- Recombinant human JAK2 (1014-1132aa) purified from E. coli
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Isotyp
- IgG2b kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- JAK2 (Janus Kinase 2 (JAK2))
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Andere Bezeichnung
- Jak2
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Hintergrund
- JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
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NCBI Accession
- NP_004963
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Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
Target
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