CD11b Antikörper (PE)

Produktnummer ABIN576541

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD11b in FACS, IHC, IP und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Pavian, Rhesusaffen und Cynomolgus.

Kurzübersicht für CD11b Antikörper (PE) (ABIN576541)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Human, Pavian, Rhesusaffen, Cynomolgus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CD11b Antikörper (PE)

Spezifität: Recognizes the human CD11b cell surface antigen, also known as the alphaM integrin. CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes. The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.

Keine Kreuzreaktivität: Katze

Aufreinigung: Protein G purified

Immunogen: Rheumatoid synovial cells and human monocytes.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL of whole blood or 10^6 cells in 100 μL. Method sheets are available on request.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled Water.

Konzentration: Lot specific

Buffer: Lyophilized, PBS, 0.09 % sodium azide, 1 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: ITGAM / CD11b

Hintergrund: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID: 3684

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation