Caspase 9 Antikörper (AA 301-305)
Kurzübersicht für Caspase 9 Antikörper (AA 301-305) (ABIN5689548)
Target
Alle Caspase 9 (CASP9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-305
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Spezifität
- This antibody detects endogenous level of total Caspase 9 protein.
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Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- Caspase 9 antibody was raised against a peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9.
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Applikationshinweise
- Western Blot: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Andere Bezeichnung
- Caspase 9
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Hintergrund
- Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
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Molekulargewicht
- 47, 37, 35 kDa
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Gen-ID
- 842
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NCBI Accession
- NP_001220
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UniProt
- P55211
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Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
Target
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