Ephrin B2 Antikörper (pTyr316)

Produktnummer ABIN5689216

Der Kaninchen Polyklonal anti-Ephrin B2 Antikörper wird verwendet zum Nachweis von Ephrin B2 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für Ephrin B2 Antikörper (pTyr316) (ABIN5689216)

Target: Ephrin B2 (EFNB2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ephrin B2 Antikörper

Bindungsspezifität: pTyr316

Spezifität: This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Ephrin-B2 (Phospho-Tyr316) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y (p) -I-V) derived from Human Ephrin-B2.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu Ephrin B2

Target: Ephrin B2 (EFNB2)

Andere Bezeichnung: Ephrin B2

Hintergrund: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Molekulargewicht: 37 kDa

Gen-ID: 1948

NCBI Accession: NP_004084

UniProt: P52799

Pathways: RTK Signalweg, Regulation of Muscle Cell Differentiation