POLD1 Antikörper

Produktnummer ABIN567776

Produktdetails anti-POLD1 Antikörper

Target: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Reaktivität: Human, Ratte, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser POLD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts with DNA polymerase delta p125 catalytic subunit (125 kDa) by Western blotting.

Aufreinigung: Protein-G Agarose Chromatography of hybridoma supernatant.

Immunogen: Recombinant full length His-Human p125.

Klon: 5G1

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu POLD1

Target: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Andere Bezeichnung: POLD1 (POLD1 Produkte)

Synonyme: CDC2 antikoerper, CRCS10 antikoerper, POLD antikoerper, 5949 antikoerper, CAA61369 antikoerper, CG5949 antikoerper, DNA Pol Delta antikoerper, Dm Poldelta antikoerper, Dmel\\CG5949 antikoerper, Poldelta antikoerper, dnapol delta antikoerper, l(3)72Ac antikoerper, cdc2 antikoerper, pold antikoerper, 125kDa antikoerper, Pol delta antikoerper, fla antikoerper, im:7139126 antikoerper, zgc:152688 antikoerper, DNA polymerase delta 1, catalytic subunit antikoerper, DNA-polymerase-delta antikoerper, polymerase (DNA directed), delta 1, catalytic subunit antikoerper, DNA polymerase delta catalytic subunit antikoerper, DNA polymerase delta antikoerper, POLD1 antikoerper, DNApol-delta antikoerper, pold1 antikoerper, LOC100456571 antikoerper, Pold1 antikoerper

Hintergrund: In eukaryotic cells, 3 types of DNA polymerases (pol), pol alpha, pol delta and pol epsilon function in accurate and efficient DNA replication. Pol delta is a heteromultimeric enzyme composed of a 125 kDa major catalytic subunit and three smaller accessory subunits. Pol delta requires a number of accessory molecules to exert its full activity. Proliferating cell nuclear antigen (PCNA) forms a doughnut-shaped trimer with a 35 Ä hole and works as the sliding clamp and replication factor C acts as the clamp loader to improve Pol delta processivity. Pol delta is also involved in nucleotide excision repair of DNA.Synonyms: DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125

Gen-ID: 5424

NCBI Accession: NP_002682

UniProt: P28340

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Chromatin Binding, Synthesis of DNA