POLD1 Antikörper (Center)

Produktnummer ABIN2855506

Produktdetails anti-POLD1 Antikörper

Target: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to DNA polymerase delta (polymerase (DNA directed), delta 1, catalytic subunit 125 kDa)
DNA polymerase delta antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DNA polymerase delta. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Rat2 , Molt-4 , 293T , A431 , HeLa , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.56 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu POLD1

Target: POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))

Andere Bezeichnung: DNA polymerase delta 1 (POLD1 Produkte)

Synonyme: CDC2 antikoerper, CRCS10 antikoerper, POLD antikoerper, 5949 antikoerper, CAA61369 antikoerper, CG5949 antikoerper, DNA Pol Delta antikoerper, Dm Poldelta antikoerper, Dmel\\CG5949 antikoerper, Poldelta antikoerper, dnapol delta antikoerper, l(3)72Ac antikoerper, cdc2 antikoerper, pold antikoerper, 125kDa antikoerper, Pol delta antikoerper, fla antikoerper, im:7139126 antikoerper, zgc:152688 antikoerper, DNA polymerase delta 1, catalytic subunit antikoerper, DNA-polymerase-delta antikoerper, polymerase (DNA directed), delta 1, catalytic subunit antikoerper, DNA polymerase delta catalytic subunit antikoerper, DNA polymerase delta antikoerper, POLD1 antikoerper, DNApol-delta antikoerper, pold1 antikoerper, LOC100456571 antikoerper, Pold1 antikoerper

Hintergrund: The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA, MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1, POLD2 (MIM 600815), POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM]

Cellular Localization: Nucleus

Molekulargewicht: 124 kDa

Gen-ID: 5424

UniProt: P28340

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Chromatin Binding, Synthesis of DNA