Rekombinanter CD40 Antikörper
Kurzübersicht für Rekombinanter CD40 Antikörper (ABIN5668237)
Target
Alle CD40 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
 - Anti-CD40 [G28.5], Mouse IgG1, kappa
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Spezifität
 - 48 kD Type I glycoprotein, a member of the TNFR superfamily primarily expressed on normal or malignant B cells or B cell lines, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
 - Protein A affinity purified
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Immunogen
 - Human erythrocyte-rosette-negative tonsillar lymphocytes.
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Isotyp
 - IgG1 kappa
 
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Applikationshinweise
 - This antibody detects CD40 by immunostaining. The original mouse IgG1 format was shown to stimulate B-cells (Bishop 2012 and references therein).
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 1 mg/mL
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Buffer
 - PBS with 0.02 % Proclin 300.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C,-20 °C
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Informationen zur Lagerung
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- CD40
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Andere Bezeichnung
 - CD40
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Hintergrund
 - TNFRS5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor CDw40, CD154R
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UniProt
 - P25942
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Pathways
 - NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
 
Target
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